School Of Science And HealthAdvanced ImmunologyWestern Sydney University Unit Code: 300905.1
Discipline: MEDICAL SCIENCE
Student Contribution Band: 3
Level: 3
Credit Points: 10
Equivalent Units
300757 - Molecular Biological of the Immune System
Prerequisite
300936 Functional Proteins and Genes
About this Unit
The human immune system is a milieu of cells, cytokines, chemokines, growth factors and cell adhesion molecules which form an elaborate molecular communication network through a number of signalling networks and molecules. The relevance of this knowledge for understanding the pathology and specific diseases of the human immune system are emphasised through the unit. This unit also provides an in depth analysis of the molecular mechanisms of cell to cell communication, cell activation, the immunological synapse, transplant rejection (including adoptive transfer experimentation), antigen presentation, B and T cell recruitment and MHC restriction. Medical and diagnostic applications of hybridoma technology, antibody engineering and advances in vaccine development are discussed. The laboratory course will develop technical and interpretative skills in relevant techniques, in particular the ImmunoCAP technology for asthma and allergy diagnosis.