School Of Science And HealthPharmacological ChemistryWestern Sydney University Unit Code: 300324.2
Discipline: CHEMICAL SCIENCES NOT ELSEWHERE CLASSIFIED
Student Contribution Band: 2
Level: 3
Credit Points: 10
Assumed Knowledge
300301 - Organic Chemistry 2. This unit is aimed at undergraduates with a grounding in chemistry and biochemistry.
Equivalent Units
J3649 - Pharmacological Chemistry
About this Unit
Contemporary medicinal chemistry relies upon a rigorously planned and rational design of drugs based upon a full understanding of both chemistry and biology. An ability to determine and define the chemical structure of the drug, its target system, its site of action and its destruction mechanisms, has allowed the scientist to systematically tailor a drug to its specific purpose using quantitative structure-activity relationships (QSAR) and this methodology is emphasised within the unit. With the accelerating development of computer-based technologies this capability has been extended further. Drugs such as cimetidine and other histamine antagonists are used to illustrate the achievement and future uses of structure-activity relationships in rational drug design, whilst the laboratory work leads to a simulated quantitative structure-activity determination relating to antimicrobials.